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......@@ -7538,7 +7538,7 @@},
author = {Papke, R. L. and Porter P., Julia K.},
author = {Papke, R. L. and Porter-Papke, J. K.},
title = {Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis.},
journal = {British journal of pharmacology},
year = {2002},
......@@ -16371,7 +16371,7 @@},
revised = {2017-03-27},
author = {Williams, P. L. and Dusenbery, D. B.},
title = {Using the nematode Caenorhabditis elegans to predict mammalian acute lethality to metallic salts.},
journal = {Toxicology and industrial health},
......@@ -17169,7 +17169,7 @@},
author = {Goldberg, F. and Grünewald, B. and Rosenboom, H. and Menzel, R.},
title = {Nicotinic acetylcholine currents of cultured Kkenyon cells from the mushroom bodies of the honey bee Aapis mellifera.},
title = {Nicotinic acetylcholine currents of cultured Kenyon cells from the mushroom bodies of the honey bee Aapis mellifera.},
journal = {The Journal of physiology},
year = {1999},
volume = {514 ( Pt 3)},
......@@ -17193,7 +17193,7 @@},
revised = {2019-05-12},
author = {Albert, J. L. and Lingle, C. J.},
title = {Activation of nicotinic acetylcholine receptors on cultured Drosophila and other insect neurones.},
journal = {The Journal of physiology},
......@@ -17219,35 +17219,6 @@},
revised = {2019-05-12},
author = {Morales-Perez, C. L. and Noviello, C. M. and Hibbs, R. E.},
title = {X-ray structure of the human α4β2 nicotinic receptor.},
journal = {Nature},
year = {2016},
volume = {538},
issue = {7625},
month = oct,
pages = {411--415},
issn = {1476-4687},
doi = {10.1038/nature19785},
abstract = {Nicotinic acetylcholine receptors are ligand-gated ion channels that mediate fast chemical neurotransmission at the neuromuscular junction and have diverse signalling roles in the central nervous system. The nicotinic receptor has been a model system for cell-surface receptors, and specifically for ligand-gated ion channels, for well over a century. In addition to the receptors' prominent roles in the development of the fields of pharmacology and neurobiology, nicotinic receptors are important therapeutic targets for neuromuscular disease, addiction, epilepsy and for neuromuscular blocking agents used during surgery. The overall architecture of the receptor was described in landmark studies of the nicotinic receptor isolated from the electric organ of Torpedo marmorata. Structures of a soluble ligand-binding domain have provided atomic-scale insights into receptor-ligand interactions, while high-resolution structures of other members of the pentameric receptor superfamily provide touchstones for an emerging allosteric gating mechanism. All available high-resolution structures are of homopentameric receptors. However, the vast majority of pentameric receptors (called Cys-loop receptors in eukaryotes) present physiologically are heteromeric. Here we present the X-ray crystallographic structure of the human α4β2 nicotinic receptor, the most abundant nicotinic subtype in the brain. This structure provides insights into the architectural principles governing ligand recognition, heteromer assembly, ion permeation and desensitization in this prototypical receptor class.},
chemicals = {Bridged Bicyclo Compounds, Heterocyclic, Ligands, Neurotransmitter Agents, Nicotinic Agonists, Pyridines, Receptors, Nicotinic, nicotinic receptor alpha4beta2, epibatidine},
citation-subset = {IM},
completed = {2017-03-07},
country = {England},
issn-linking = {0028-0836},
keywords = {Binding Sites; Bridged Bicyclo Compounds, Heterocyclic, chemistry, metabolism; Crystallography, X-Ray; Humans; Ion Transport; Ligands; Models, Molecular; Neurotransmitter Agents, chemistry, metabolism; Nicotinic Agonists, chemistry, metabolism; Protein Structure, Quaternary; Pyridines, chemistry, metabolism; Receptors, Nicotinic, chemistry, metabolism},
mid = {NIHMS812379},
nlm-id = {0410462},
owner = {NLM},
pii = {nature19785},
pmc = {PMC5161573},
pmid = {27698419},
pubmodel = {Print-Electronic},
pubstatus = {ppublish},
revised = {2018-11-13},
author = {Althoff, T. and Hibbs, R. E. and Banerjee, S. and Gouaux, E.},
title = {X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.},
......@@ -17324,7 +17295,6 @@},
volume = {305},
number = {9},
pages = {720--730},
__markedentry = {[monik:]},
publisher = {Wiley Online Library},
......@@ -17333,7 +17303,6 @@},
title = {Caenorhabditis elegans Feeding Behaviors},
booktitle = {Oxford Research Encyclopedia of Neuroscience},
year = {2017},
__markedentry = {[monik:6]},
......@@ -17342,4 +17311,36 @@},
ctldash_repeated_names = {no},
author = {Han, H. and Yang, Shi-H. and Phillips, W. D.},
title = {Overexpression of rapsyn modifies the intracellular trafficking of acetylcholine receptors},
journal = {Journal of neuroscience research},
year = {2000},
volume = {60},
number = {2},
pages = {155--163},
__markedentry = {[monik:]},
publisher = {Wiley Online Library},
author = {Visvanathan, Archunan},
title = {The influence of the MuSK system and the L25 transgene on the Neuromuscular Junction},
year = {2015},
__markedentry = {[monik:]},
school = {University of Sydney},
author = {Bourne, Y. and Talley, T. T. and Hansen, S. B. and Taylor, P. and Marchot, P.},
title = {Crystal structure of a Cbtx--AChBP complex reveals essential interactions between snake $\alpha$-neurotoxins and nicotinic receptors},
journal = {The EMBO journal},
year = {2005},
volume = {24},
number = {8},
pages = {1512--1522},
__markedentry = {[monik:6]},
publisher = {John Wiley \& Sons, Ltd},
@Comment{jabref-meta: databaseType:biblatex;}
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