diff --git a/poetry.lock b/poetry.lock
index 01b82fdcf2c7b7ca66f6b08b6b4f3c7f5418e2af..d2080574050672d5b36e9f53327e8ee7bfa6619d 100644
--- a/poetry.lock
+++ b/poetry.lock
@@ -281,6 +281,14 @@ category = "main"
 optional = false
 python-versions = ">=3.6"
 
+[[package]]
+name = "numpy"
+version = "1.20.1"
+description = "NumPy is the fundamental package for array computing with Python."
+category = "main"
+optional = false
+python-versions = ">=3.7"
+
 [[package]]
 name = "packaging"
 version = "20.9"
@@ -839,7 +847,7 @@ testing = ["pytest (>=3.5,!=3.7.3)", "pytest-checkdocs (>=1.2.3)", "pytest-flake
 [metadata]
 lock-version = "1.1"
 python-versions = "^3.6"
-content-hash = "25e36fbd14f3335226afa65b2d5f62e37fcdf526b4f743bbfff42e6d3a11ba18"
+content-hash = "f35c140d13741413ff816520486bec91842863ee8991b5177b11c0bb8a76ff05"
 
 [metadata.files]
 alabaster = [
@@ -1116,6 +1124,30 @@ numpy = [
     {file = "numpy-1.19.5-cp39-cp39-win_amd64.whl", hash = "sha256:0eef32ca3132a48e43f6a0f5a82cb508f22ce5a3d6f67a8329c81c8e226d3f6e"},
     {file = "numpy-1.19.5-pp36-pypy36_pp73-manylinux2010_x86_64.whl", hash = "sha256:a0d53e51a6cb6f0d9082decb7a4cb6dfb33055308c4c44f53103c073f649af73"},
     {file = "numpy-1.19.5.zip", hash = "sha256:a76f502430dd98d7546e1ea2250a7360c065a5fdea52b2dffe8ae7180909b6f4"},
+    {file = "numpy-1.20.1-cp37-cp37m-macosx_10_9_x86_64.whl", hash = "sha256:ae61f02b84a0211abb56462a3b6cd1e7ec39d466d3160eb4e1da8bf6717cdbeb"},
+    {file = "numpy-1.20.1-cp37-cp37m-manylinux1_i686.whl", hash = "sha256:65410c7f4398a0047eea5cca9b74009ea61178efd78d1be9847fac1d6716ec1e"},
+    {file = "numpy-1.20.1-cp37-cp37m-manylinux1_x86_64.whl", hash = "sha256:2d7e27442599104ee08f4faed56bb87c55f8b10a5494ac2ead5c98a4b289e61f"},
+    {file = "numpy-1.20.1-cp37-cp37m-manylinux2010_i686.whl", hash = "sha256:4ed8e96dc146e12c1c5cdd6fb9fd0757f2ba66048bf94c5126b7efebd12d0090"},
+    {file = "numpy-1.20.1-cp37-cp37m-manylinux2010_x86_64.whl", hash = "sha256:ecb5b74c702358cdc21268ff4c37f7466357871f53a30e6f84c686952bef16a9"},
+    {file = "numpy-1.20.1-cp37-cp37m-manylinux2014_aarch64.whl", hash = "sha256:b9410c0b6fed4a22554f072a86c361e417f0258838957b78bd063bde2c7f841f"},
+    {file = "numpy-1.20.1-cp37-cp37m-win32.whl", hash = "sha256:3d3087e24e354c18fb35c454026af3ed8997cfd4997765266897c68d724e4845"},
+    {file = "numpy-1.20.1-cp37-cp37m-win_amd64.whl", hash = "sha256:89f937b13b8dd17b0099c7c2e22066883c86ca1575a975f754babc8fbf8d69a9"},
+    {file = "numpy-1.20.1-cp38-cp38-macosx_10_9_x86_64.whl", hash = "sha256:a1d7995d1023335e67fb070b2fae6f5968f5be3802b15ad6d79d81ecaa014fe0"},
+    {file = "numpy-1.20.1-cp38-cp38-manylinux1_i686.whl", hash = "sha256:60759ab15c94dd0e1ed88241fd4fa3312db4e91d2c8f5a2d4cf3863fad83d65b"},
+    {file = "numpy-1.20.1-cp38-cp38-manylinux1_x86_64.whl", hash = "sha256:125a0e10ddd99a874fd357bfa1b636cd58deb78ba4a30b5ddb09f645c3512e04"},
+    {file = "numpy-1.20.1-cp38-cp38-manylinux2010_i686.whl", hash = "sha256:c26287dfc888cf1e65181f39ea75e11f42ffc4f4529e5bd19add57ad458996e2"},
+    {file = "numpy-1.20.1-cp38-cp38-manylinux2010_x86_64.whl", hash = "sha256:7199109fa46277be503393be9250b983f325880766f847885607d9b13848f257"},
+    {file = "numpy-1.20.1-cp38-cp38-manylinux2014_aarch64.whl", hash = "sha256:72251e43ac426ff98ea802a931922c79b8d7596480300eb9f1b1e45e0543571e"},
+    {file = "numpy-1.20.1-cp38-cp38-win32.whl", hash = "sha256:c91ec9569facd4757ade0888371eced2ecf49e7982ce5634cc2cf4e7331a4b14"},
+    {file = "numpy-1.20.1-cp38-cp38-win_amd64.whl", hash = "sha256:13adf545732bb23a796914fe5f891a12bd74cf3d2986eed7b7eba2941eea1590"},
+    {file = "numpy-1.20.1-cp39-cp39-macosx_10_9_x86_64.whl", hash = "sha256:104f5e90b143dbf298361a99ac1af4cf59131218a045ebf4ee5990b83cff5fab"},
+    {file = "numpy-1.20.1-cp39-cp39-manylinux2010_i686.whl", hash = "sha256:89e5336f2bec0c726ac7e7cdae181b325a9c0ee24e604704ed830d241c5e47ff"},
+    {file = "numpy-1.20.1-cp39-cp39-manylinux2010_x86_64.whl", hash = "sha256:032be656d89bbf786d743fee11d01ef318b0781281241997558fa7950028dd29"},
+    {file = "numpy-1.20.1-cp39-cp39-manylinux2014_aarch64.whl", hash = "sha256:66b467adfcf628f66ea4ac6430ded0614f5cc06ba530d09571ea404789064adc"},
+    {file = "numpy-1.20.1-cp39-cp39-win32.whl", hash = "sha256:12e4ba5c6420917571f1a5becc9338abbde71dd811ce40b37ba62dec7b39af6d"},
+    {file = "numpy-1.20.1-cp39-cp39-win_amd64.whl", hash = "sha256:9c94cab5054bad82a70b2e77741271790304651d584e2cdfe2041488e753863b"},
+    {file = "numpy-1.20.1-pp37-pypy37_pp73-manylinux2010_x86_64.whl", hash = "sha256:9eb551d122fadca7774b97db8a112b77231dcccda8e91a5bc99e79890797175e"},
+    {file = "numpy-1.20.1.zip", hash = "sha256:3bc63486a870294683980d76ec1e3efc786295ae00128f9ea38e2c6e74d5a60a"},
 ]
 packaging = [
     {file = "packaging-20.9-py2.py3-none-any.whl", hash = "sha256:67714da7f7bc052e064859c05c595155bd1ee9f69f76557e21f051443c20947a"},
diff --git a/pyproject.toml b/pyproject.toml
index 2584ca74d12e5b2aff8d6a848e72010fc7f44d5e..3db3f8c8f0a01eab9c44aae1ad77a53337924108 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -28,7 +28,10 @@ pycgtool = "pycgtool.__main__:main"
 [tool.poetry.dependencies]
 python = "^3.6"
 wheel = "^0.35.1"
-numpy = "^1.19.1"
+numpy = [
+    { version = "^1.19.1", python = "<3.7" },  # Support for Python 3.6 was dropped in 1.20
+    { version = "^1.20.0", python = ">=3.7" }  # But 1.20 should resolve issue with MDTraj on macOS
+]
 cython = "^0.29.21"
 mdtraj = "^1.9.5"
 rich = "^9.2.0"